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Preventive Neurology is blog devoted to medical, lifestyle and wellness practices that are designed to avert and avoid neurological disease. For example, screening for hypertension and treating it before it causes diseases such as stroke or dementia, is good preventive neurology. Preventive neurology takes a proactive approach to patient care; prevention is better than having to deal with consequences of neurological disease. 

The activities on this blog are a public engagement tool to support several preventive neurology research initiatives within the Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, Queen Mary University London.  

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#BrainHealth: another reason to hate margerine

Information rarely changes health outcomes on its own, which is why we need policy #PreventiveNeurology #BrainHealth
Although we have known about the cardiovascular risks associated with the consumption of trans fatty acids (TFAs) for decades little has been done by individuals to reduce their consumption. Therefore when the state of New York put in place restrictions on their use in 11 counties between 2007 and 2011 they set-up an experiment. This experiment now reports out: the study below included 25 counties and compared cardiovascular outcomes in the TFA non-restricted populations of 14 counties with the populations in the 11 TFA restricted counties. Three or more years after restrictions were put in place the people living in the counties with TFA restrictions experienced a significant decline in combined myocardial infarction and stroke events (-6.2%) compared with the TFA non-restricted populations. 

I sincerely hope you appreciate the significance of these findings? 

Lessons lea…

#BrainHealth: you are what you eat?

If you take #BrainHealth seriously you need to focus on diet.


Do you buy into 'you are what you eat'? This ambitious systematic literature review has identified 10 foods and 7 nutrients with evidence for causal cardio-metabolic effects. Any intervention that reduces your vascular risk burden should reduce all-cause dementia and improve your Brain Health. 

The foods that were found to have protective effects: fruitsvegetablesbeans/legumesnuts/seedswhole grainsfishyogurtfibreseafood omega-3spolyunsaturated fatspotassiumThe food found to have harmful effects:  unprocessed red meatsprocessed meatssugar-sweetened beveragesglycemic load (sugar or carbohydrates)trans-fatssodium/salt. There is nothing new here and most of this should be obvious to you and is currently included in mots dietary guidelines. The elephant in the room is economics; in modern economies people eat what they can afford. Modifying the nation's diet is going to need a rethink about how we encourage a healthy die…

#DietSpeak: slaying the high fat dogma

It is about time we started rejigging our diets away from carbs to high-fat foods. #DietSpeak
Although this is not a randomised control trial we can use observational studies to draw conclusions. It is becoming increasingly clear that high carbohydrate intake is bad for you and that a high-fat diet is better for you. 
In this large macronutrient study higher carbohydrate intake is associated with an increased risk of total mortality whereas intake of total fat and each type of fat was associated with lower risk of total mortality. 
This is just the latest piece of evidence showing a high-fat diet is good for you. 

Dehghan et al. Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study. Lancet. 2017 Aug 28. pii: S0140-6736(17)32252-3. 
BACKGROUND: The relationship between macronutrients and cardiovascular disease and mortality is controversial. Most available data are from European and Nort…